Sex Differences in Early Cognitive Development After Prenatal Exposure to Opioids.

ABSTRACT:

Objective

Prenatal opioid exposure has been linked with impaired cognitive development, with boys potentially at elevated risk. In the present study, we examined cognitive and language development of children prenatally exposed to opioids, with an additional focus on sex differences.

Methods

A sample of 378 children (n = 194 girls and n = 184 boys) aged 1.2-42.8 months was drawn from the Danish Family Outpatient Clinic database. Developmental outcomes were assessed using the Bayley-III cognitive and language scales, and substance exposure was determined with urine screening and/or verbal report. Children exposed to opioids (n = 94) were compared to children with no prenatal substance exposure (n = 38), and children exposed to alcohol (n = 131) or tobacco (n = 115). Group and

SUBMITTER: Skumlien M 

PROVIDER: S-EPMC7233842 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature