A Child with Seckel Syndrome and Arterial Stenosis: Case Report and Literature Review.

ABSTRACT:

Background

Seckel syndrome is a rare genetic disorder with autosomal recessive inheritance. It is characterized by dysmorphic features, intrauterine and postnatal growth restriction, microcephaly and mental retardation. Although cardiovascular complications are not prevalent in this syndrome, severe sinus bradycardia, hypertension and brain vasculopathy are reported. Here, for the first time, we describe a case of lower extremity arterial occlusion in a case of Seckel syndrome.

Case presentation

An 8-year-old girl with the characteristic features of Seckel syndrome was admitted to the children's hospital with the complaint of left lower extremity pain and a deep ulcer on her left shin. On examination, the left extremity was cooler than the other side, with a bluish color. Do

SUBMITTER: Saeidi M 

PROVIDER: S-EPMC7234957 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature