Primary Immunodeficiencies in a Mesoregion of Sao Paulo, Brazil: Epidemiologic, Clinical, and Geospatial Approach.

ABSTRACT: Background: Primary immunodeficiencies (PIDs) are rare genetic disorders leading to immunologic abnormalities that can affect different organs and systems. We determined the epidemiology, clinical, and geospatial characteristics of PID disorders among patients diagnosed over a 5 year period in a reference hospital covering a mesoregion in São Paulo, Brazil. Methods: A retrospective analysis of 39 patients with recognizable PIDs according to the criteria of the European Society of Primary Immunodeficiencies were enrolled. Thirty-four patients came from outpatient immunodeficiency clinics and five patients from active search. Demographic, clinical, and immunologic data were collected, and maps were constructed using a geographic information system. Results: The ratio of

SUBMITTER: Boton Pereira DH 

PROVIDER: S-EPMC7235164 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature