Reactivation of Motor-Related Gamma Activity in Human NREM Sleep.

ABSTRACT: Models of memory consolidation posit a central role for reactivation of brain activity patterns during sleep, especially in non-Rapid Eye Movement (NREM) sleep. While such "replay" of recent waking experiences has been well-demonstrated in rodents, electrophysiological evidence of reactivation in human sleep is still largely lacking. In this intracranial study in patients with epilepsy (N = 9) we explored the spontaneous electroencephalographic reactivation during sleep of spatial patterns of brain activity evoked by motor learning. We first extracted the gamma-band (60-140 Hz) patterns underlying finger movements during a tapping task and underlying no-movement during a short rest period just prior to the task, and trained a binary classifier to discriminate between motor movements vs. re

SUBMITTER: Eichenlaub JB 

PROVIDER: S-EPMC7235414 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature