Radiological differences between subtypes of WHO 2016 grade II-III gliomas: a systematic review and meta-analysis.

ABSTRACT:

Background

Isocitrate dehydrogenase (IDH) mutation and 1p/19q-codeletion are oncogenetic alterations with a positive prognostic value for diffuse gliomas, especially grade II and III. Some studies have suggested differences in biological behavior as reflected by radiological characteristics. In this paper, the literature regarding radiological characteristics in grade II and III glioma subtypes was systematically evaluated and a meta-analysis was performed.

Methods

Studies that addressed the relationship between conventional radiological characteristics and IDH mutations and/or 1p/19q-codeletions in newly diagnosed, grade II and III gliomas of adult patients were included. The "3-group analysis" compared radiological characteristics between the WHO 2016 glioma subtypes (IDH-

SUBMITTER: van Lent DI 

PROVIDER: S-EPMC7236393 | biostudies-literature | 2020 Jan-Dec

REPOSITORIES: biostudies-literature