Cancer-Related Cognitive Outcomes Among Older Breast Cancer Survivors in the Thinking and Living With Cancer Study.

ABSTRACT:

Purpose

To determine treatment and aging-related effects on longitudinal cognitive function in older breast cancer survivors.

Methods

Newly diagnosed nonmetastatic breast cancer survivors (n = 344) and matched controls without cancer (n = 347) 60 years of age and older without dementia or neurologic disease were recruited between August 2010 and December 2015. Data collection occurred during presystemic treatment/control enrollment and at 12 and 24 months through biospecimens; surveys; self-reported Functional Assessment of Cancer Therapy-Cognitive Function; and neuropsychological tests that measured attention, processing speed, and executive function (APE) and learning and memory (LM). Linear mixed-effects models tested two-way interactions of treatment group (control, chem

SUBMITTER: Mandelblatt JS 

PROVIDER: S-EPMC7237199 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature