Synergistic Cues from Diverse Bacteria Enhance Multicellular Development in a Choanoflagellate.

ABSTRACT: Bacteria regulate the life histories of diverse eukaryotes, but relatively little is known about how eukaryotes interpret and respond to multiple bacterial cues encountered simultaneously. To explore how a eukaryote might respond to a combination of bioactive molecules from multiple bacteria, we treated the choanoflagellate Salpingoeca rosetta with two sets of bacterial cues, one that induces mating and another that induces multicellular development. We found that simultaneous exposure to both sets of cues enhanced multicellular development in S. rosetta, eliciting both larger multicellular colonies and an increase in the number of colonies. Thus, rather than conveying conflicting sets of information, these distinct bacterial cues synergize to augment multicellular development. This study

SUBMITTER: Ireland EV 

PROVIDER: S-EPMC7237790 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature