Sleep Irregularity and Risk of Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis.

ABSTRACT:

Background

The cardiovascular system exhibits strong circadian rhythms to maintain normal functioning. Irregular sleep schedules, characterized by high day-to-day variability in sleep duration or timing, represent possibly milder but much more common and chronic disruption of circadian rhythms in the general population than shift work.

Objectives

This study aimed to prospectively examine the association between sleep regularity and risk of cardiovascular disease (CVD).

Methods

In MESA (Multi-Ethnic Study of Atherosclerosis), 1,992 participants free of CVD completed 7-day wrist actigraphy for sleep assessment from 2010 to 2013 and were prospectively followed through 2016. The study assessed sleep regularity using the SD of actigraphy-measured sleep duration and sleep-o

SUBMITTER: Huang T 

PROVIDER: S-EPMC7237955 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature