Longitudinal follow-up with VIM thalamic deep brain stimulation for dystonic or essential tremor.

ABSTRACT:

Objective

To assess longitudinal tremor outcomes with ventral intermediate nucleus deep brain stimulation (VIM DBS) in patients with dystonic tremor (DT) and to compare with DBS outcomes in essential tremor (ET).

Methods

We retrospectively investigated VIM DBS outcomes for 163 patients followed at our center diagnosed with either DT or ET. The Fahn-Tolosa-Marin tremor rating scale (TRS) was used to assess change in tremor and activities of daily living (ADL) at 6 months, 1 year, 2-3 years, 4-5 years, and ≥6 years after surgery.

Results

Twenty-six patients with DT and 97 patients with ET were analyzed. Compared to preoperative baseline, there were significant improvements in TRS motor up to 4-5 years (52.2%; p = 0.032) but this did not reach statistical signific

SUBMITTER: Tsuboi T 

PROVIDER: S-EPMC7238918 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature