Effect of adjuvant radiotherapy in elderly patients with breast cancer.

ABSTRACT:

Background

Radiotherapy (RT) is of critical importance in the locoregional management of early breast cancer. Although RT is routinely used following breast conserving surgery (BCS), patients may occasionally be effectively treated with BCS alone. Currently, the selection of patients undergoing BCS who do not need breast irradiation is under investigation. With the advancement of personalized medicine, there is an increasing interest in reduction of aggressive treatments especially in older women. The primary objective of this study was to identify elderly patients who may forego breast irradiation after BCS without measurable consequences on local tumor growth and survival.

Methods

We analyzed 2384 early breast cancer patients aged 70 and older who were treated in 17 German

SUBMITTER: Stueber TN 

PROVIDER: S-EPMC7239665 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature