Long-term survival outcomes following laparoscopic surgery for clinical stage 0/I rectal carcinoma.

ABSTRACT:

Aim

To clarify and evaluate the long-term outcomes of laparoscopic surgery for clinical stage 0/I rectal carcinoma patients.

Methods

This single-arm phase II trial involved accredited surgeons from 43 Japanese institutions. Patients were registered preoperatively. The planned sample size was 490. The primary endpoint was overall survival, and long-term outcomes were evaluated.

Results

A total of 495 patients were registered between February 2008 and August 2010. Eight patients (1.6%) required conversion to open surgery. Sphincter-preserving procedures were performed in 477 (97%) patients. Positive radial resection margin was found in two (0.4%) patients. Of 490 patients, 22, 314, 38, 115, and one patient had final pathological stages (p-stage) 0, I, II, III, and IV, r

SUBMITTER: Ito M 

PROVIDER: S-EPMC7240150 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature