Miniaturized high-throughput synthesis and screening of responsive hydrogels using nanoliter compartments.

ABSTRACT: The traditional pipeline of hydrogel development includes individual one-by-one synthesis and characterization of hydrogels. This approach is associated with the disadvantages of low-throughput and high cost. As an alternative approach to classical one-by-one synthesis, high-throughput development of hydrogels is still tremendously under-represented in the field of responsive material development, despite the urgent requirement for such techniques. Here, we report a platform that combines highly miniaturized hydrogel synthesis with screening for responsive properties in a high-throughput manner. The platform comprises a standard glass slide patterned with 1 ​× ​1 ​mm hydrophilic regions separated by superhydrophobic liquid-impermeable barriers, thus allowing deposition of various precursor

SUBMITTER: Rosenfeld A 

PROVIDER: S-EPMC7240218 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature