Definitive re-irradiation of locally recurrent esophageal cancer after trimodality therapy in patients with a poor performance status.

ABSTRACT: There are few treatment guidelines for locally recurrent esophageal cancer after trimodality treatment (pre-operative chemoradiation followed by surgery) in patients with a poor performance status. The purpose of this single institutional, retrospective study was to evaluate the clinical outcomes and toxicities of definitive-intent re-irradiation for patients with recurrent esophageal cancer with a poor performance status [ECOG (Eastern Cooperative Oncology Group) ≥2]. Seven patients were identified with a median age of 74 years (range, 61-81 years). Four patients were ECOG 2 and three patients were ECOG 3. The median follow-up time after re-irradiation was 49 months. The median interval between initial radiotherapy and re-treatment was 32 months. Six patients received concurrent chemother

SUBMITTER: W Kim D 

PROVIDER: S-EPMC7241232 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature