S1 Subunit and Host Proteases as Potential Therapeutic Avenues for the Treatment of COVID-19.

ABSTRACT: The novel corona virus (SARS-CoV-2) that causes severe acute respiratory syndrome, now called COVID-19 initially originated in Wuhan city of China and later spread across borders and infected more than five million people and killed over 3.4 lakh people all over the globe. This disease has been announced as pandemic by WHO. So far, there has been not much progress in terms of drug development for fighting against this deadliest virus, also no existing drugs has been reported completely effective for COVID-19 treatment owing to lack of effective therapeutic targets and a broad understanding of the viral behavior in target cell. Some reports have found and confirmed that SARS-CoV-2 like others SARS-CoVs utilizes angiotensin converting enzyme-2 receptor for making entry into target cell by bi

SUBMITTER: Arafah A 

PROVIDER: S-EPMC7241389 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature