Copy number variants and fixed duplications among 198 rhesus macaques (Macaca mulatta).

ABSTRACT: The rhesus macaque is an abundant species of Old World monkeys and a valuable model organism for biomedical research due to its close phylogenetic relationship to humans. Copy number variation is one of the main sources of genomic diversity within and between species and a widely recognized cause of inter-individual differences in disease risk. However, copy number differences among rhesus macaques and between the human and macaque genomes, as well as the relevance of this diversity to research involving this nonhuman primate, remain understudied. Here we present a high-resolution map of sequence copy number for the rhesus macaque genome constructed from a dataset of 198 individuals. Our results show that about one-eighth of the rhesus macaque reference genome is composed of recently dupli

SUBMITTER: Braso-Vives M 

PROVIDER: S-EPMC7241854 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature