Acute ischaemic stroke alters the brain's preference for distinct dynamic connectivity states.

ABSTRACT: Acute ischaemic stroke disturbs healthy brain organization, prompting subsequent plasticity and reorganization to compensate for the loss of specialized neural tissue and function. Static resting state functional MRI studies have already furthered our understanding of cerebral reorganization by estimating stroke-induced changes in network connectivity aggregated over the duration of several minutes. In this study, we used dynamic resting state functional MRI analyses to increase temporal resolution to seconds and explore transient configurations of motor network connectivity in acute stroke. To this end, we collected resting state functional MRI data of 31 patients with acute ischaemic stroke and 17 age-matched healthy control subjects. Stroke patients presented with moderate to severe han

SUBMITTER: Bonkhoff AK 

PROVIDER: S-EPMC7241954 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature