Reference Ranges for Left Ventricular Curvedness and Curvedness-Based Functional Indices Using Cardiovascular Magnetic Resonance in Healthy Asian Subjects.

ABSTRACT: Curvature-based three-dimensional cardiovascular magnetic resonance (CMR) allows regional function characterization without an external spatial frame of reference. However, introduction of this modality into clinical practice is hampered by lack of reference values. We aim to establish normal ranges for 3D left ventricular (LV) regional parameters in relation to age and gender for 171 healthy subjects. LV geometrical reconstruction and automatic calculation of regional parameters were implemented by in-house software (CardioWerkz) using stacks of short-axis cine slices. Parameter normal ranges were stratified by gender and age categories (≤44, 45-64, 65-74 and 75-84 years). Our software had excellent intra- and inter-observer agreement. Ageing was significantly associated with increases in

SUBMITTER: Zhao X 

PROVIDER: S-EPMC7242400 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature