Predictors of CD4 count changes over time among children who initiated highly active antiretroviral therapy in Ethiopia.

ABSTRACT:

Introduction

Human immunodeficiency virus (HIV) infection results in a gradual depletion of immune function, particularly CD4 cells. The CD4 assessment plays a significant role in assessing treatment responses and clinical decision-making for patients on combination antiretroviral therapy (ART) in resource-limited settings. However, new data on CD4 count changes are scarce; the volatility of CD4 counts after initiation of ART over time remains largely uncharacterized. This study aimed to identify the predictors of CD4 changes over time among HIV-infected children who began ART in Amhara, Ethiopia.

Methods

A retrospective follow-up study was performed. A total of 983 HIV-infected children who initiated ART in government hospitals in the Amhara region between 2010 and 2016 wer

SUBMITTER: Birhan TY 

PROVIDER: S-EPMC7243309 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature