Ontology highlight
ABSTRACT:
SUBMITTER: Chandrashekar A
PROVIDER: S-EPMC7243369 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Science (New York, N.Y.) 20200520 6505
An understanding of protective immunity to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is critical for vaccine and public health strategies aimed at ending the global coronavirus disease 2019 (COVID-19) pandemic. A key unanswered question is whether infection with SARS-CoV-2 results in protective immunity against reexposure. We developed a rhesus macaque model of SARS-CoV-2 infection and observed that macaques had high viral loads in the upper and lower respiratory tract, humora ...[more]