Unraveling the Association Between Gait and Mortality-One Step at a Time.

ABSTRACT:

Background

Slowness of walking is one of the very first signs of aging and is considered a marker for overall health that is strongly associated with mortality risk. In this study, we sought to disentangle the clinical drivers of the association between gait and mortality.

Methods

We included 4,490 participants of the Rotterdam Study who underwent a gait assessment between 2009 and 2015 and were followed-up for mortality until 2018. Gait was assessed with an electronic walkway and summarized into the domains Rhythm, Phases, Variability, Pace, Tandem, Turning, and Base of Support. Cox models adjusted for age, sex, and height were built and consecutively adjusted for six categories of health indicators (lifestyle, musculoskeletal, cardiovascular, pulmonary, metabolic, and neur

SUBMITTER: Dommershuijsen LJ 

PROVIDER: S-EPMC7243583 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature