Prognostic value of comorbidity indices and lung diseases in early rheumatoid arthritis: a UK population-based study.

ABSTRACT:

Objectives

We assessed comorbidity burden in people with RA at diagnosis and early disease (3 years) and its association with early mortality and joint destruction. The association between lung disease and mortality in RA is not well studied; we also explored this relationship.

Methods

From a contemporary UK-based population (n = 1, 475 762) we identified a cohort with incident RA (n = 6591). The prevalence of comorbidities at diagnosis of RA and at 3 years was compared with age- and gender-matched controls (n = 6591). In individuals with RA we assessed the prognostic value of the Charlson Comorbidity Index and Rheumatic Disease Comorbidity Index calculated at diagnosis for all-cause mortality and joint destruction (with joint surgery as a surrogate marker). We separately ev

SUBMITTER: Nikiphorou E 

PROVIDER: S-EPMC7244778 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature