Community-acquired Bacterial Meningitis in Adults With Cerebrospinal Fluid Leakage.

ABSTRACT:

Background

Cerebrospinal fluid (CSF) leakage is a risk factor for developing bacterial meningitis.

Methods

We analyzed episodes of community-acquired bacterial meningitis associated with CSF leakage from a prospective nationwide cohort study.

Results

CSF leakage was identified in 65 episodes of 2022 episodes (3%) in 53 patients. The cause of CSF leakage was identified in 49 of 65 episodes (75%), which most commonly consisted of ear-nose-throat surgery (19 of 49 episodes [29%]) and remote head trauma (15 of 49 episodes [23%]). The episode was a recurrent meningitis episode in 38 patients (59%). Of the recurrent episodes, 27 had known CSF leakage (71%) of whom 20 (53%) had previous surgery aiming to close the leak. Nine patients (38%) with known CSF leakage had been vac

SUBMITTER: Ter Horst L 

PROVIDER: S-EPMC7245152 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature