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ABSTRACT: Background
In ARDS patients, mechanical ventilation should minimize ventilator-induced lung injury. The mechanical power which is the energy per unit time released to the respiratory system according to the applied tidal volume, PEEP, respiratory rate, and flow should reflect the ventilator-induced lung injury. However, similar levels of mechanical power applied in different lung sizes could be associated to different effects. The aim of this study was to assess the role both of the mechanical power and of the transpulmonary mechanical power, normalized to predicted body weight, respiratory system compliance, lung volume, and amount of aerated tissue on intensive care mortality.Methods
Retrospective analysis of ARDS patients previously enrolled in seven published studies. A
SUBMITTER: Coppola S
PROVIDER: S-EPMC7245621 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature