Lymphopenia in severe coronavirus disease-2019 (COVID-19): systematic review and meta-analysis.

ABSTRACT:

Objective

Clinical and laboratory biomarkers to predict the severity of coronavirus disease 2019 (COVID-19) are essential in this pandemic situation of which resource allocation must be urgently prepared especially in the context of respiratory support readiness. Lymphocyte count has been a marker of interest since the first COVID-19 publication. We conducted a systematic review and meta-analysis in order to investigate the association of lymphocyte count on admission and the severity of COVID-19. We would also like to analyze whether patient characteristics such as age and comorbidities affect the relationship between lymphocyte count and COVID-19.

Methods

Comprehensive and systematic literature search was performed from PubMed, SCOPUS, EuropePMC, ProQuest, Cochrane Central

SUBMITTER: Huang I 

PROVIDER: S-EPMC7245646 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature