Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders.

ABSTRACT: Recent extensive evidence indicates that air pollution, in addition to causing respiratory and cardiovascular diseases, may also negatively affect the brain and contribute to central nervous system diseases. Air pollution is comprised of ambient particulate matter (PM) of different sizes, gases, organic compounds, and metals. An important contributor to PM is represented by traffic-related air pollution, mostly ascribed to diesel exhaust (DE). Epidemiological and animal studies have shown that exposure to air pollution may be associated with multiple adverse effects on the central nervous system. In addition to a variety of behavioral abnormalities, the most prominent effects caused by air pollution are oxidative stress and neuro-inflammation, which are seen in both humans and animals, and

SUBMITTER: Costa LG 

PROVIDER: S-EPMC7245732 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature