Could venous thromboembolism and major bleeding be indicators of lung cancer mortality? A nationwide database study.

ABSTRACT:

Background

Venous thromboembolism (VTE) is highly prevalent in cancer patients and can cause severe morbidity. VTE treatment is essential, but anticoagulation increases the risk of major bleeding. The purpose was to evaluate the impact of VTE and major bleeding on survival and to identify significant risk factors for these events in lung cancer patients.

Methods

Data were extracted from a permanent sample of the French national health information system (including hospital and out-of-hospital care) from 2009 to 2016. All episodes of VTE and major bleeding events within one year after cancer diagnosis were identified. A Cox model was used to analyse the effect of VTE and major bleeding on the patients' one-year survival. VTE and major bleeding risk factors were analysed with

SUBMITTER: Howlett J 

PROVIDER: S-EPMC7245783 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature