Evidence that human and equine erythrocytes could have significant roles in the transport and delivery of amino acids to organs and tissues.

ABSTRACT: Erythrocytes have a well-defined role in the gaseous exchange of oxygen and carbon dioxide in the mammalian body. The erythrocytes can contain more than half of the free amino acids present in whole blood. Based on measures showing that venous erythrocyte levels of amino acids are much less than arterial erythrocyte levels, it has previously been proposed that erythrocytes also play a role in the delivery of amino acids to tissues in the body. This role has been dismissed because it has been assumed that to act as an amino acid transport vehicle, the erythrocytes should release their entire amino acid content in the capillary beds at the target tissues with kinetic studies showing that this would take too long to achieve. This investigation set out to investigate whether the equine erythro

SUBMITTER: Thorn B 

PROVIDER: S-EPMC7246245 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature