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The end-expiratory occlusion test for detecting preload responsiveness: a systematic review and meta-analysis.


ABSTRACT:

Background

We performed a systematic review and meta-analysis of studies assessing the end-expiratory occlusion test (EEXPO test)-induced changes in cardiac output (CO) measured by any haemodynamic monitoring device, as indicators of preload responsiveness.

Methods

MEDLINE, EMBASE and Cochrane Database were screened for original articles. Bivariate random-effects meta-analysis determined the Area under the Summary Receiver Operating Characteristic (AUSROC) curve of EEXPO test-induced changes in CO to detect preload responsiveness, as well as pooled sensitivity and specificity and the best diagnostic threshold.

Results

Thirteen studies (530 patients) were included. Nine studies were performed in the intensive care unit and four in the operating room. The pooled sensiti

SUBMITTER: Gavelli F 

PROVIDER: S-EPMC7246264 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature