Biphasic human insulin 30 thrice daily, is it reasonable?

ABSTRACT:

Objective

To evaluate the efficacy and safety of thrice daily Biphasic Human Insulin 30 (BHI 30) versus the traditional twice-daily regimen in type 2 diabetes mellitus (T2DM) patients. It's a cross over single clinical study. Twenty-two diabetic patients who were already using BHI 30 in twice or thrice daily regimens with or without metformin were included. At the 1st interval; patients continued on their usual insulin regimen as twice or thrice daily injections with adjustment of insulin doses guided by their glucose readings. On the 2nd interval; patients were switched to the other regimen with the same total daily insulin dose redistributed.

Results

There was a significant decrease in HbA1c level (p < 0.05) at the end of the first 3 months of trial regardless on which reg

SUBMITTER: Saadeh NA 

PROVIDER: S-EPMC7247174 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature