Impact of sex and gender on COVID-19 outcomes in Europe.

ABSTRACT:

Background

Emerging evidence from China suggests that coronavirus disease 2019 (COVID-19) is deadlier for infected men than women with a 2.8% fatality rate being reported in Chinese men versus 1.7% in women. Further, sex-disaggregated data for COVID-19 in several European countries show a similar number of cases between the sexes, but more severe outcomes in aged men. Case fatality is highest in men with pre-existing cardiovascular conditions. The mechanisms accounting for the reduced case fatality rate in women are currently unclear but may offer potential to develop novel risk stratification tools and therapeutic options for women and men.

Content

The present review summarizes latest clinical and epidemiological evidence for gender and sex differences in COVID-19 from Euro

SUBMITTER: Gebhard C 

PROVIDER: S-EPMC7247289 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature