Association of dietary vitamin K and risk of coronary heart disease in middle-age adults: the Hordaland Health Study Cohort.

ABSTRACT:

Objective

The role of vitamin K in the regulation of vascular calcification is established. However, the association of dietary vitamins K1 and K2 with risk of coronary heart disease (CHD) is inconclusive.

Design

Prospective cohort study.

Setting

We followed participants in the community-based Hordaland Health Study from 1997 - 1999 through 2009 to evaluate associations between intake of vitamin K and incident (new onset) CHD. Baseline diet was assessed by a past-year food frequency questionnaire. Energy-adjusted residuals of vitamin K1 and vitamin K2 intakes were categorised into quartiles.

Participants

2987 Norwegian men and women, age 46-49 years.

Methods

Information on incident CHD events was obtained from the nationwide Cardiovascular Disease in Nor

SUBMITTER: Haugsgjerd TR 

PROVIDER: S-EPMC7247390 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature