Role of Endocannabinoids in Energy-Balance Regulation in Participants in the Postobese State-a PREVIEW Study.

ABSTRACT: Endocannabinoids are suggested to play a role in energy balance regulation. We aimed to investigate associations of endocannabinoid concentrations during the day with energy balance and adiposity and interactions with 2 diets differing in protein content in participants in the postobese phase with prediabetes. Participants (n = 38) were individually fed in energy balance with a medium protein (MP: 15:55:30% of energy from protein:carbohydrate:fat) or high-protein diet (HP: 25:45:30% energy from P:C:F) for 48 hours in a respiration chamber. Associations between energy balance, energy expenditure, respiratory quotient, and endocannabinoid concentrations during the day were assessed. Plasma-concentrations of anandamide (AEA), oleoylethanolamide (OEA), palmitoyethanolamide (PEA), and pregnenol

SUBMITTER: Drummen M 

PROVIDER: S-EPMC7247554 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature