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Repurposing Quaternary Ammonium Compounds as Potential Treatments for COVID-19.

ABSTRACT: The COVID-19 pandemic has highlighted an important role for drug repurposing. Quaternary ammonium compounds such as ammonium chloride, cetylpyridinium and miramistin represent widely accessible antiseptic molecules with well-known broad-spectrum antiviral activities and represent a repurposing opportunity as therapeutics against SARS-CoV-2.

SUBMITTER: Baker N 

PROVIDER: S-EPMC7247743 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature

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Repurposing Quaternary Ammonium Compounds as Potential Treatments for COVID-19.

Baker Nancy N   Williams Antony J AJ   Tropsha Alexander A   Ekins Sean S  

Pharmaceutical research 20200525 6

The COVID-19 pandemic has highlighted an important role for drug repurposing. Quaternary ammonium compounds such as ammonium chloride, cetylpyridinium and miramistin represent widely accessible antiseptic molecules with well-known broad-spectrum antiviral activities and represent a repurposing opportunity as therapeutics against SARS-CoV-2. ...[more]

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