Body Weight Variability Increases Dementia Risk Among Older Adults: A Nationwide Population-Based Cohort Study.

ABSTRACT: Background: Recent growing evidences suggest that body weight (Bwt) variability, a repeated loss and regain of weight within a specific period, causes metabolic disturbances and can be a marker for poor homeostasis. Although there have been many studies about the association between Bwt variability and various health status, its association with the incidence of dementia among elderly people has not been examined. Methods: We performed a retrospective elderly cohort study from 19,987 participants with mean age 73 years old in the Korean National Health Insurance Service. We examined the risk of incident dementia, including Alzheimer's dementia and vascular dementia, according to the quartile of Bwt variability, represented as coefficient of variation (Bwt-CV), SD (Bwt-SD), an

SUBMITTER: Roh E 

PROVIDER: S-EPMC7247844 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature