Variable symptomatic and neurophysiologic response to HD-tDCS in a case series with posttraumatic stress disorder.

ABSTRACT: Chronic Posttraumatic stress disorder (PTSD), characterized by symptoms of re-experiencing, hyperarousal, and avoidance, is challenging to treat as a significant proportion of patients remain symptomatic following even empirically supported interventions. The current case series investigated the effects of up to 10 sessions of high definition transcranial direct current stimulation (HD-tDCS) on symptoms of PTSD. Participants received HD-tDCS that targeted the right lateral temporal cortex (LTC; center cathode placed over T8), given this region's potential involvement in symptoms of re-experiencing and, possibly, hyperarousal. Five of the six enrolled patients completed at least 8 sessions. Of these five, four showed improvement in symptoms of re-experiencing after HD-tDCS. This improvement

SUBMITTER: Hampstead BM 

PROVIDER: S-EPMC7247940 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature