Development of 3D-Printed Sulfated Chitosan Modified Bioresorbable Stents for Coronary Artery Disease.

ABSTRACT: Bioresorbable polymeric stents have attracted great interest for coronary artery disease because they can provide mechanical support first and then disappear within a desired time period. The conventional manufacturing process is laser cutting, and generally they are fabricated from tubular prototypes produced by injection molding or melt extrusion. The aim of this study is to fabricate and characterize a novel bioresorbable polymeric stent for treatment of coronary artery disease. Polycaprolactone (PCL) is investigated as suitable material for biomedical stents. A rotary 3D printing method is developed to fabricate the polymeric stents. Surface modification of polymeric stent is performed by immobilization of 2-N, 6-O-sulfated chitosan (26SCS). Physical and chemical characterization resul

SUBMITTER: Qiu T 

PROVIDER: S-EPMC7248363 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature