An Association of an eBURST Group With Triazole Resistance of Candida tropicalis Blood Isolates.

ABSTRACT: Candidemia, a bloodstream infection caused by genus Candida, has a high mortality rate. Candida albicans was previously reported to be the most common causative species among candidemia patients. However, during the past 10 years in Thailand, Candida tropicalis has been recovered from blood more frequently than C. albicans. The cause of this shift in the prevalence of Candida spp. remains unexplored. We conducted in vitro virulence studies and antifungal susceptibility profiles of 48 C. tropicalis blood isolates collected during 2015-2017. To compare to global isolates of C. tropicalis, multilocus sequence typing (MLST), a minimum spanning tree, and an eBURST analysis were also conducted. C. tropicalis and C. albicans we

SUBMITTER: Tulyaprawat O 

PROVIDER: S-EPMC7248567 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature