Ontology highlight
ABSTRACT:
SUBMITTER: Risbjerg RS
PROVIDER: S-EPMC7249386 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Risbjerg Rasmus Strøm RS Hansen Mie Vennize MV Sørensen Anne Sofie AS Kragstrup Tue Wenzel TW
Experimental hematology & oncology 20200525
This letter describes the potential effect of B cell depletion on immune related adverse events associated with immune checkpoint inhibition. B cell depleting agents such as rituximab reduce B cell to plasma cell differentiation and antibody production. This treatment strategy is used in several immune mediated inflammatory diseases such as rheumatoid arthritis and small vessel vasculitis. The immune related adverse events associated with immune checkpoint inhibition resemble immune mediated inf ...[more]