Porin Expression Profiles in Haemaphysalis longicornis Infected With Babesia microti.

ABSTRACT: The porin gene is widely disseminated in various organisms and has a pivotal role in the regulation of pathogen infection in blood-sucking arthropods. However, to date, information on the porin gene from the Haemaphysalis longicornis tick, an important vector of human and animal diseases, remains unknown. In this study, we identified the porin gene from H. longicornis and evaluated its expression levels in Babesia microti-infected and -uninfected H. longicornis ticks at developmental stages. We also analyzed porin functions in relation to both tick blood feeding and Babesia infection and the relationship between porin and porin-related apoptosis genes such as B-cell lymphoma (Bcl), cytochrome comp

SUBMITTER: Zheng W 

PROVIDER: S-EPMC7249857 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature