Clinical evidence for repurposing chloroquine and hydroxychloroquine as antiviral agents: a systematic review.

ABSTRACT:

Background

Repurposing hydroxychloroquine (HCQ) and chloroquine (CQ) as antiviral agents is a re-emerging topic with the advent of new viral epidemics.

Aims

To summarize evidence from human clinical studies for using HCQ or CQ as antiviral agents for any viral infection.

Sources

PubMed, EMBASE, Scopus, Web of Science for published studies without time or language restrictions; Cochrane Clinical Trial Registry and Chinese Clinical Trials Registry for trials registered after 2015; MedRxiv for preprints within the last 12 months.

Content

Study eligibility criteria were interventional and prospective observational studies (with or without a control group). Participants were adults and children with a confirmed viral infection. Interventions included the use of CQ o

SUBMITTER: Rodrigo C 

PROVIDER: S-EPMC7250111 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature