Validation of the ANCA-associated vasculitis patient-reported outcomes (AAV-PRO) questionnaire.

ABSTRACT:

Objectives

To finalise and validate a disease-specific patient-reported outcome (PRO) measure: the ANCA-associated vasculitis patient-reported outcome (AAV-PRO) questionnaire. Using a 35-item candidate questionnaire developed following 50 qualitative interviews in the UK, USA and Canada, a longitudinal survey was conducted to determine the final scale structure and validate the AAV-PRO.

Methods

Participants were recruited via Vasculitis UK and the Vasculitis Patient-Powered Research Network. The 35-item candidate questionnaire was completed at baseline and 3 months; UK participants completed the EuroQol-5D-5L (EQ-5D-5L), while US participants completed a test-retest exercise, 3-5 days after baseline. Scale structure was defined using exploratory factor analysis (EFA) and Ras

SUBMITTER: Robson JC 

PROVIDER: S-EPMC7250143 | biostudies-literature | 2018 Aug

REPOSITORIES: biostudies-literature