A prospective observational cohort study of posterior tibial nerve stimulation in patients with multiple sclerosis: design and methods.

ABSTRACT:

Background

Posterior tibial nerve stimulation (PTNS) is a promising treatment for lower urinary tract symptoms (LUTS) in patients with MS. However, long term data focusing on PTNS impact on health-related quality of life (HRQOL), bowel and bladder symptoms are lacking. This paper describes a study protocol that examines the extended efficacy of PTNS on MS related bladder and bowel symptoms and resulting HRQOL.

Methods/design

This is a single-centered, prospective, longitudinal, observational cohort study of patients with MS who suffer from LUTS and are refractory to two prior treatment modalities. Participants who have elected to pursue PTNS therapy for LUTS will be eligible. The primary outcome is the median number of urinary frequency and incontinence episodes on a 3-day v

SUBMITTER: Lane GI 

PROVIDER: S-EPMC7251681 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature