Durability of bioprosthetic aortic valves in patients under the age of 60 years - rationale and design of the international INDURE registry.

ABSTRACT: BACKGROUND:There is an ever-growing number of patients requiring aortic valve replacement (AVR). Limited data is available on the long-term outcomes and structural integrity of bioprosthetic valves in younger patients undergoing surgical AVR. METHODS:The INSPIRIS RESILIA Durability Registry (INDURE) is a prospective, open-label, multicentre, international registry with a follow-up of 5 years to assess clinical outcomes of patients younger than 60 years who undergo surgical AVR using the INSPIRIS RESILIA aortic valve. INDURE will be conducted across 20-22 sites in Europe and Canada and intends to enrol minimum of 400 patients. Patients will be included if they are scheduled to undergo AVR with or without concomitant root replacement and/or coronary bypass surgery. The primary objectives are

SUBMITTER: Meuris B 

PROVIDER: S-EPMC7251702 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature