Patterns of recurrence in anal cancer: a detailed analysis.

ABSTRACT:

Background

Anal cancer is a rare disease, which might be the reason for the "one size fits all" approach still used for radiotherapy target contouring. To refine and individualize future guidelines, detailed and contemporary pattern of recurrence studies are needed.

Methods

Consecutive anal cancer patients, all treated with curative intent intensity-modulated radiotherapy (IMRT), were retrospectively studied (n = 170). Data was extracted from medical records and radiological images. Radiotherapy planning CT's and treatment plans were reviewed, and recurrences were mapped and categorized according to radiation dose.

Results

The mean dose to the primary tumor was 59.0 Gy. With a median follow-up of 50 months (range 14-117 months), 5-year anal cancer specific survival wa

SUBMITTER: Nilsson MP 

PROVIDER: S-EPMC7251738 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature