The association between genetic variants in lactotransferrin and dental caries: a meta- and gene-based analysis.

ABSTRACT:

Background

The pathogenesis of dental caries remains unclear, with increasing evidence suggesting that genetic susceptibility plays an essential role. Previous studies have reported the association between genetic polymorphisms in lactotransferrin (LTF) and the risk of dental caries with inconsistent results.

Methods

A systematic literature search of the PubMed, Cochrane Library, HuGE and Google Scholar databases was performed by two authors independently for papers published before December 5, 2019 on the association between genetic variants in LTF and the risk of dental caries. We adopted the subsequent inclusion criteria to assess study eligibility: 1) The studies were based on human subjects; 2) the presence of dental caries should be screened for in both the case group

SUBMITTER: Li X 

PROVIDER: S-EPMC7251739 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature