Atypical somatosensory-motor cortical response during vowel vocalization in spasmodic dysphonia.

ABSTRACT: OBJECTIVE:Spasmodic dysphonia (SD) is a debilitating voice/speech disorder without an effective cure. To obtain a better understanding of the underlying cortical neural mechanism of the disease we analyzed electroencephalographic (EEG) signals of people with SD during voice production. METHOD:Ten SD individuals and 10 healthy volunteers produced 50 vowel vocalization epochs of 2500 ms duration. Two EEG features were derived: (1) event-related change in spectral power during vocalization relative to rest, (2) inter-regional spectral coherence. RESULTS:During early vocalization (500-1000 ms) the SD group showed significantly larger alpha band spectral power over the left motor cortex. During late vocalization (1000-2500 ms) SD patients showed a significantly larger gamma band coherence betwe

SUBMITTER: Khosravani S 

PROVIDER: S-EPMC7251941 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature