Cis- and Trans-Regulatory Variations in the Domestication of the Chili Pepper Fruit.

ABSTRACT: The process of domestication requires the rapid transformation of the wild morphology into the cultivated forms that humans select for. This process often takes place through changes in the regulation of genes, yet, there is no definite pattern on the role of cis- and trans-acting regulatory variations in the domestication of the fruit among crops. Using allele-specific expression and network analyses, we characterized the regulatory patterns and the inheritance of gene expression in wild and cultivated accessions of chili pepper, a crop with remarkable fruit morphological variation. We propose that gene expression differences associated to the cultivated form are best explained by cis-regulatory hubs acting through trans-regulatory cascades. We show that in cultivated chili, the expressio

SUBMITTER: Diaz-Valenzuela E 

PROVIDER: S-EPMC7253206 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature