Sex differences in associations of socioemotional dispositions measured in childhood and adolescence with brain white matter microstructure 12 years later.

ABSTRACT: Predictive associations were estimated between socioemotional dispositions measured at 10-17 years using the Child and Adolescent Dispositions Scale (CADS) and future individual differences in white matter microstructure measured at 22-31 years of age. Participants were 410 twins (48.3% monozygotic) selected for later neuroimaging by oversampling on risk for psychopathology from a representative sample of child and adolescent twins. Controlling for demographic covariates and total intracranial volume (TICV), each CADS disposition (negative emotionality, prosociality, and daring) rated by one of the informants (parent or youth) significantly predicted global fractional anisotropy (FA) averaged across the major white matter tracts in brain in adulthood, but did so through significant interac

SUBMITTER: Lahey BB 

PROVIDER: S-EPMC7253690 | biostudies-literature | 2020

REPOSITORIES: biostudies-literature