Epidemiology of adult and pediatric Burkitt lymphoma in Canada: sequelae of the HIV epidemic.

ABSTRACT:

Background

Although the pathogenesis and epidemiology of endemic Burkitt lymphoma (bl) have been extensively studied, the epidemiologic landscape of sporadic and immunodeficiency-associated bl in North America remains poorly understood.

Methods

We used 3 distinct population-based cancer registries to retrospectively study bl incidence and mortality in Canada. Data for patient sex; age at the time of diagnosis; and reporting province, city, and forward sortation area (fsa, the first three characters of a postal code) were analyzed.

Results

During 1992-2010, 1420 patients with bl in Canada were identified (incidence rate: 2.40 cases per million patient-years), of which 71.1% were male patients. Mean age at diagnosis was 55.5 ± 20.8 years. A bimodal incidence by age dist

SUBMITTER: Roy SF 

PROVIDER: S-EPMC7253744 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature