How is best supportive care provided in clinical trials for patients with advanced cancer? A review of registered protocols of clinical trials.

ABSTRACT:

Background

In 2012, 11 standards describing best supportive care (bsc) in clinical trials in advanced cancer were defined through consensus statements. The consensus included 15 key components. Our objective was to analyze whether clinical trials that involved patients with advanced cancer and that included bsc in at least 1 arm met the standards and contained the key components.

Methods

We reviewed clinical trials registered in ClinicalTrials.gov, the isrctn (International Standard Randomised Controlled Trial Number) registry, the EU Clinical Trials Register, and the International Clinical Trials Registry Platform for 2012-2018. We selected only phase iii studies in patients with advanced cancer that included bsc in at least 1 arm. We describe the characteristics of the tri

SUBMITTER: Sanz Rubiales A 

PROVIDER: S-EPMC7253756 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature